Participating research institutes
University of Geneva
The two Rheumatology laboratories are affiliated to the Division of Rheumatology, Department of Internal Medicine Specialities and the Department of Pathology-Immunology at the University of Geneva School of Medicine.
In the group led by Professor Cem Gabay research is primarily focused on the pathogenesis of inflammatory responses in arthritis and other inflammatory diseases, with a special interest in the field of cytokines, in particular the interleukin-1 family. We are also leading and participating in clinical trials with anti-cytokine therapies in patients with rheumatic diseases.
In the group led by Professor Monique Gannagé, which was established by the IRR, the focus is on the effects of autophagy in arthritis diseases. Autophagy is a fundamental process for degrading and recycling cellular components. The research focuses on the contribution of the pathway in regulating immune and inflammatory responses.
University of Lausanne
The Department of Biochemistry (DB) is part of the Faculty of Biology and Medicine of the University of Lausanne and researches in medicine, biology and immunology.
The research aims to contribute to the understanding of immune processes and elimination of immunological disorders by studying inflammation, cell differentiation and cell signalling, with a strong focus on the discovery and functional characterization of molecular pathways. A second line of research, with the WHO Immunology Research and Training center, studies parasitic diseases and the immune response they elicit.
University of Zürich
The Center of Experimental Rheumatology is at the Department of Rheumatology, University Hospital Zürich. The Center studies the molecular and cellular aspects of rheumatic diseases in a clinical setting. The European League Against Rheumatism (EULAR) has awarded it the status of a “Center of Excellence in Rheumatology” since 2005. This 5-year award, which has been granted 3 times successfully, is based on the record of scientific publication. IRR has been pivotal for this publication record, as it was for six European funded projects.